EFFECT OF NATURAL ENHANCERS IN TRANSDERMAL PERMEATION OF FLUOXETINE
نویسندگان
چکیده
منابع مشابه
Effect of Chemical Enhancers in Transdermal Permeation of Alfuzosin Hydrochloride
The objective of the present study is to explore the efficient chemical penetration enhancer among the various enhancers available in overcoming the stratum corneum barrier in transdermal delivery of Alfuzosin hydrochloride (AH). The different enhancers were incorporated in 2% Carbopol gel which was selected as a control and evaluated by in vitro diffusion studies through dialysis membrane and ...
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Lisinopril dihydrate (angiotensin converting enzyme inhibitor) is a lysine derivative of enalaprilat and does not require hydrolysis to exert pharmacological activity. It has an extensive hepatic first pass metabolism resulting in a bioavailabil-ity of 6-60%. To overcome the poor bioavailability of the drug, transdermal patches have been prepared. The present study also aims at optimizati...
متن کاملDahiya et al: Effect of Permeation Enhancers on Transdermal Delivery of Venlafaxine from Carboopol Gel
In this study, we investigated the effect of different permeation enhancers at different concentrations viz. oleic acid, olive oil and castor oil from transdermal gel for transdermal delivery of venlafaxine, a newer antidepressant. It is a first line drug in the treatment of depression and inhibits brain serotonin and norepinephrine neuronal reuptake. It is also used in the treatment of anxiety...
متن کاملA Review: Effect of Permeation Enhancers on the Penetration Mechanism of Transdermal Gel
Transdermal systems are non-invasive, convenient, and inexpensive and can be self-administered. They can provide sustained plasma concentration profile for long periods of time. The systems can greatly improve patient compliance through avoidance of first-past metabolism, improved bioavailability, reduction of systemic side effects and dosing schedule. In the past three decades, transdermal dru...
متن کاملEffect of Permeation Enhancers on Transdermal Delivery of Venlafaxine Hydrochloride from Carbopol Gel
In this study, we investigated the effect of different permeation enhancers at different concentrations viz. oleic acid, olive oil and castor oil from transdermal gel for transdermal delivery of venlafaxine, a newer antidepressant. It is a first line drug in the treatment of depression and inhibits brain serotonin and norepinephrine neuronal reuptake. It is also used in the treatment of anxiety...
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ژورنال
عنوان ژورنال: International Journal of Innovations in Biological and Chemical Sciences
سال: 2016
ISSN: 2047-9093
DOI: 10.20530/ijibcs_9_31-38